Social and economic deprivation impacts on rates of psychotic illness

Urban life is known to impact on rates of schizophrenia, however, until now, very little was known about the influential factors that led to this increased risk. A new study from the department elucidates some of the key determinants that lead to increased risk for psychotic illness in urban areas, highlighting the role of  social and economic  inequality. Results [...]

Dr Graham Murray appointed Unversity Lecturer in Psychiatry

The Department would like to extend congratulations to Dr Graham Murray who has recently been appointed as University Lecturer in Psychiatry and honorary consultant psychiatrist. Julia Graham caught up with him to discuss his research and his plans for the new role. Dr Murray first came to Cambridge in 2000 to begin his clinical psychiatry training, [...]

Modafinil effects on schizophrenia: A systematic review

  Modafinil is a central nervous system wake promoting agent that has been recently used as a cognitive enhancer, although its neural functions are not entirely understood. In a recent publication in Neuropharmacology led by Dr Linda Scoriels, the effects of modafinil in cognitive and emotional function are reviewed. Modafinil was created in the 1970s, and despite it [...]

Cognitive Impairment in Schizophrenia: The 2012 Paykel Lecture

The 2012 Paykel lecture in Psychiatry, entitled  ’The Cognitive Impairment in Schizophrenia: Neural Basis and Clinical Relevance”, was given this week by Professor Eileen Joyce, Professor of Neuropsychiatry at UCL.  Prof Joyce, who is also Chair of the British Neuropsychiatry Association, began with a short history of schizophrenia research, from Freud through the sociology of the 1960s [...]

Early infection link to schizophrenia

Schizophrenia is a psychiatric disorder for which the cause remains unclear. In a recent set of findings, Dr Golam Khandaker and colleagues have confirmed that exposure to certain infections before birth or during early childhood can increase the chances of developing schizophrenia as an adult. In a systematic review recently published in Psychological Medicine, Dr Khandaker [...]

Epigenomics paper offers insight into the role of prenatal nutrition and schizophrenia

A article  in an upcoming issue of Epigenomics offers a perspective on the link between prenatal nutrition and schizophrenia. The paper, led by  Dr James Kirkbride from the Department of Psychiatry in collaboration with other groups, reviews the evidence for links between prenatal nutrition and  epigenetic changes in schizophrenia. The role of epigenetics, which refers to alterations in [...]

Charting the past to anticipate the future

A new Cambridge-led study, published today in PLoS One, has examined the past 60 years of incidence data on psychotic disorders in England in the hope that the data can reveal clues about the possible social factors which appear to underpin such conditions. The systematic review, which was led by Dr James Kirkbride, of the [...]