Professor John T O’Brien is Professor of Old Age Psychiatry in the Department of Psychiatry at the University of Cambridge and Honorary Consultant Old Age Psychiatrist within Cambridgeshire and Peterborough NHS Trust and Cambridge University Hospitals NHS Trust. He is also a NIHR Emeritus Senior Investigator and a Fellow of the UK Academy of Medical Sciences. His research interests include: the use of brain imaging, especially multi-modal MRI and PET, as a biomarker in dementia. He has particular interests in dementia with Lewy bodies and the role of vascular factors in dementia and depression. He leads the Old Age Psychiatry research group who are undertaking a variety of clinical cross-sectional and longitudinal cohort studies as well as laboratory based experimental studies and several clinical trials. He has published over 550 peer reviewed papers on these topics and was a member of the National Institute for Health and Clinical Excellence (NICE), British Association of Psychopharmacology and the European Federation Neurological Sciences (EFNS) Dementia Guideline groups. His other current roles include being the NIHR National Specialty Lead for Dementia and Treasurer of the International Vas-Cog Society.
Dr Ben Underwood is Assistant Professor in Applied and Translational Old Age Psychiatry at the University of Cambridge and an Honorary Consultant Old Age Psychiatrist. He did his PhD in the molecular neurogenetics of Huntington’s disease with Professor David Rubinsztein in Cambridge with a view to finding new therapeutic strategies in dementia. This has continued to be his major research interest and he has recently published the first clinical trial of an autophagy up-regulating drug in Huntington’s disease. He is the clinical director of the older people and adult community directorate of CPFT and also clinical director of the Windsor unit at Fulbourn, a unit which delivers clinical trials on the NIHR portfolio. He is the clinical lead for division 4 of the NIHR clinical research network for East Anglia and a consultant old age psychiatrist in Cambridge.
Dr Leonidas Chouliaras is Assistant Professor in Old Age Psychiatry at University of Cambridge. He has previously been an NIHR Academic Clinical Fellow in Psychiatry at Oxford. He completed his PhD on dementia epigenetics at Maastricht University in the Netherlands and medical school at the Aristotle University of Thessaloniki in Greece. His research interests include the role of epigenetic mechanisms in neurodegeneration and particularly in Lewy Body Dementia and Alzheimer’s disease. His projects focus on genome-wide profiling of DNA methylation and hydroxymethylation in post-mortem brain tissues and also in peripheral blood. Exploring disease driven changes in the epigenetic landscape has the potential to improve our understanding of the pathophysiology of neurodegenerative disorders and aid in the identification of novel pathways as therapeutic targets.
Professor Li Su is Professor of Neuroimaging at the Neuroscience Institute, University of Sheffield. He has a joint appointment at the Department of Psychiatry, University of Cambridge as Principal Research Fellow (Professor Grade 11) and is Head of the Artificial Intelligence and Computational Neuroscience Group. He holds a senior research fellowship from Alzheimer’s Research UK (ARUK). He is member of AI for Health panel at UKRI, national steering group for NIHR BRC Imaging Network and specialist committee at NICE. Prof Su is regional co-lead for the National Network for the Application of Data Science and AI to Dementia Research (DEMON). He is also a member of the Grant Review Committee for Lewy Body Society and Alzheimer’s Society’s Research Strategy Council. He combines innovative and original computational methods with the state-of-the-art brain imaging techniques (MEG/EEG, 7T MRI and PET) in understanding, detecting and developing treatments for brain conditions.
Dr Annabel Price trained in medicine at the Royal Free Hospital School of Medicine, London before training in General Adult, Old Age and Liaison Psychiatry on the Maudsley Hospital Rotation London. Annabel went on to be a Clinical Lecturer in Palliative Care Psychiatry. Currently Annabel is a Consultant Liaison Psychiatrist, Older People’s Team, Addenbrooke’s Hospital and a teaching specialist in palliative care. Her research interests include: Mental health at the end of life and the interface between mental health and assisted dying.