His research interests include the role of epigenetic mechanisms in neurodegeneration and particularly in Lewy Body Dementia and Alzheimer’s disease. His projects focus on genome-wide profiling of DNA methylation and hydroxymethylation in post-mortem brain tissues and also in peripheral blood. Exploring disease driven changes in the epigenetic landscape has the potential to improve our understanding of the pathophysiology of neurodegenerative disorders and aid in the identification of novel pathways as therapeutic targets.
I previously worked in the Division of Population Medicine in Cardiff University on a population-level cohort. I completed a PhD in Health Psychology in Trinity College Dublin in Ireland. My research interests are in health communication and information, public health and disease progression.
I am a trainee Neurologist and my research interests include using PET scanning to learn more about the brain changes that occur during life in illnesses such as frontotemporal dementia.
Dr Nicastro is a Swiss board-certified Neurologist with a strong interest in dementia and movement disorders. He was awarded with a 2-year research funding from Geneva University Hospitals.
His research focuses on molecular and structural MRI imaging in dementia with Lewy bodies and Parkinson disease, especially as early diagnostic markers and for differential diagnosis. In Cambridge, he will be participating in the NIMROD and TENDeR studies, as well as a new project involving synaptic imaging.
Mrs Allison Bentley, Dementia with Lewy Bodies Lead Research Nurse
Dr Robert Dudas, Consultant and Visiting Researcher
Dr Yujing Huang, Postdoctoral Visiting Researcher
Dr Elijah Mak, Research Associate
Dr Marius Mada, Postdoctoral Research Associate
Dr James Stefaniak, Academic Clinical Fellow (University of Manchester)
Thais Minett, Visiting Researcher (Cambridge University Hospitals)
Dr Elie Matar, Visiting Researcher (The University of Sydney)
Dr Stephen Carter, Senior Research Associate