Tari, B., Ben Yehuda, M., Laurell, A. A. S., Ritchie, K., Dauvilliers, Y., Ritchie, C. W., Lawlor, B., Naci, L., Muniz Terrera, G., Malhotra, P., Watermeyer, T., Dudas, R., Underwood, B. R., O’Brien, J. T., Raymont, V., & Koychev, I. (2023). The indirect relationship between sleep and cognition in the PREVENT cohort: identifying targets for intervention. Frontiers in Sleep, 2, 1226824. https://doi.org/10.3389/frsle.2023.1226824

Dounavi, M.-E., Mak, E., Swann, P., Low, A., Muniz-Terrera, G., McKeever, A., Pope, M., Williams, G. B., Wells, K., Lawlor, B., Naci, L., Malhotra, P., Mackay, C., Koychev, I., Ritchie, K., Su, L., Ritchie, C. W., & O’Brien, J. T. (2023). Differential association of cerebral blood flow and anisocytosis in APOE ε4 carriers at midlife. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 43(10), 1672–1684. https://doi.org/10.1177/0271678X231173587

Kucikova, L., Zeng, J., Muñoz-Neira, C., Muniz-Terrera, G., Huang, W., Gregory, S., Ritchie, C., O’Brien, J., & Su, L. (2023). Genetic risk factors of Alzheimer’s Disease disrupt resting-state functional connectivity in cognitively intact young individuals. Journal of Neurology, 270(10), 4949–4958. https://doi.org/10.1007/s00415-023-11809-9

Kouli, A., Spindler, L. R. B., Fryer, T. D., Hong, Y. T., Malpetti, M., Aigbirhio, F. I., White, S. R., Camacho, M., O’Brien, J. T., & Williams-Gray, C. H. (2023). Neuroinflammation is linked to dementia risk in Parkinson’s disease. Brain : A Journal of Neurology, awad322. https://doi.org/10.1093/brain/awad322

Durcan, R., Roberts, G., Hamilton, C. A., Donaghy, P. C., Howe, K., Colloby, S. J., Allan, L. M., Firbank, M., Lawley, S., Petrides, G. S., Lloyd, J. J., Taylor, J.-P., O’Brien, J. T., & Thomas, A. J. (2023). Serial Nigrostriatal Dopaminergic Imaging in Mild Cognitive Impairment With Lewy Bodies, Alzheimer Disease, and Age-Matched Controls. Neurology, 101(12), e1196–e1205. https://doi.org/10.1212/WNL.0000000000207621

Butters, E., Srinivasan, S., O’Brien, J. T., Su, L., & Bale, G. (2023). A promising tool to explore functional impairment in neurodegeneration: A systematic review of near-infrared spectroscopy in dementia. Ageing Research Reviews, 90, 101992. https://doi.org/10.1016/j.arr.2023.101992

Giorgio, J., Tanna, A., Malpetti, M., White, S. R., Wang, J., Baker, S., Landau, S., Tanaka, T., Chen, C., Rowe, J. B., O’Brien, J., Fripp, J., Breakspear, M., Jagust, W., & Kourtzi, Z. (2023). A robust harmonization approach for cognitive data from multiple aging and dementia cohorts. Alzheimer’s & Dementia (Amsterdam, Netherlands), 15(3), e12453. https://doi.org/10.1002/dad2.12453

Chouliaras, L., & O’Brien, J. T. (2023). The use of neuroimaging techniques in the early and differential diagnosis of dementia. Molecular Psychiatry. https://doi.org/10.1038/s41380-023-02215-8

Malpetti, M., Cope, T. E., Street, D., Jones, P. S., Hezemans, F. H., Mak, E., Tsvetanov, K. A., Rittman, T., Bevan-Jones, W. R., Patterson, K., Passamonti, L., Fryer, T. D., Hong, Y. T., Aigbirhio, F. I., O’Brien, J. T., & Rowe, J. B. (2023). Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia. Brain : A Journal of Neurology, 146(8), 3221–3231. https://doi.org/10.1093/brain/awad078

Wright, L. M., Donaghy, P. C., Burn, D. J., Taylor, J.-P., O’Brien, J. T., Yarnall, A. J., Matthews, F. E., Firbank, M. J., Thomas, A. J., & Lawson, R. A. (2023). Predicting cognitive decline using neuropsychiatric symptoms in prodromal Lewy body dementia: A longitudinal study. Parkinsonism & Related Disorders, 113, 105762. https://doi.org/10.1016/j.parkreldis.2023.105762

Hamilton, C. A., O’Brien, J., Heslegrave, A., Laban, R., Donaghy, P., Durcan, R., Lawley, S., Barnett, N., Roberts, G., Firbank, M., Taylor, J.-P., Zetterberg, H., & Thomas, A. (2023). Plasma biomarkers of neurodegeneration in mild cognitive impairment with Lewy bodies. Psychological Medicine, 1–9. https://doi.org/10.1017/S0033291723001952

Wardlaw, J. M., Woodhouse, L. J., Mhlanga, I. I., Oatey, K., Heye, A. K., Bamford, J., Cvoro, V., Doubal, F. N., England, T., Hassan, A., Montgomery, A., O’Brien, J. T., Roffe, C., Sprigg, N., Werring, D. J., & Bath, P. M. (2023). Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2)  Randomized Clinical Trial. JAMA Neurology, 80(7), 682–692. https://doi.org/10.1001/jamaneurol.2023.1526

McKiernan, E., Su, L., & O’Brien, J. (2023). MRS in neurodegenerative dementias, prodromal syndromes and at-risk states: A systematic review of the literature. NMR in Biomedicine, 36(7), e4896. https://doi.org/10.1002/nbm.4896

Gonzalez, M. C., Tovar-Rios, D. A., Alves, G., Dalen, I., Williams-Gray, C. H., Camacho, M., Forsgren, L., Bäckström, D., Lawson, R. A., Macleod, A. D., Counsell, C. E., Paquet, C., DeLena, C., D’Antonio, F., Pilotto, A., Padovani, A., Blanc, F., Falup-Pecurariu, C., Lewis, S. J. G., … Maple-Grødem, J. (2023). Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson’s Disease Dementia. Movement Disorders Clinical Practice, 10(6), 980–986. https://doi.org/10.1002/mdc3.13752

Donaghy, P. C., Hamilton, C., Durcan, R., Lawley, S., Barker, S., Ciafone, J., Barnett, N., Olsen, K., Firbank, M., Roberts, G., Lloyd, J., Allan, L. M., Saha, R., McKeith, I. G., O’Brien, J. T., Taylor, J.-P., & Thomas, A. J. (2023). Clinical symptoms in mild cognitive impairment with Lewy bodies: Frequency, time of onset, and discriminant ability. European Journal of Neurology, 30(6), 1585–1593. https://doi.org/10.1111/ene.15783

Holland, N., Jones, P. S., Savulich, G., Naessens, M., Malpetti, M., Whiteside, D. J., Street, D., Swann, P., Hong, Y. T., Fryer, T. D., Rittman, T., Mulroy, E., Aigbirhio, F. I., Bhatia, K. P., O’Brien, J. T., & Rowe, J. B. (2023). Longitudinal Synaptic Loss in Primary Tauopathies: An In Vivo [ ¹¹ C ] UCB‐J Positron Emission Tomography Study. Movement Disorders, mds.29421. https://doi.org/10.1002/mds.29421

Omar, R., Kuo, L., Costafreda, S. G., Hall, A., Forbes, M., O’Brien, J. T., & Schilder, A. G. M. (2023). Managing comorbid cognitive impairment and hearing loss in older adults: a UK survey of audiology and memory services. Age and Ageing, 52(5), afad080. https://doi.org/10.1093/ageing/afad080

Ferrari-Souza, J. P., Lussier, F. Z., Leffa, D. T., Therriault, J., Tissot, C., Bellaver, B., Ferreira, P. C. L., Malpetti, M., Wang, Y.-T., Povala, G., Benedet, A. L., Ashton, N. J., Chamoun, M., Servaes, S., Bezgin, G., Kang, M. S., Stevenson, J., Rahmouni, N., Pallen, V., … Pascoal, T. A. (2023). APOEε4 associates with microglial activation independently of Aβ plaques and tau tangles. Science Advances, 9(14), eade1474. https://doi.org/10.1126/sciadv.ade1474

Schumacher, J., Ray, N. J., Hamilton, C. A., Bergamino, M., Donaghy, P. C., Firbank, M., Watson, R., Roberts, G., Allan, L., Barnett, N., O’Brien, J. T., Thomas, A. J., & Taylor, J. (2023). Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer’s disease. Alzheimer’s & Dementia, alz.13034. https://doi.org/10.1002/alz.13034

Ray, N. J., Lawson, R. A., Martin, S. L., Sigurdsson, H. P., Wilson, J., Galna, B., Lord, S., Alcock, L., Duncan, G. W., Khoo, T. K., O’Brien, J. T., Burn, D. J., Taylor, J.-P., Rea, R. C., Bergamino, M., Rochester, L., & Yarnall, A. J. (2023). Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson’s disease. Brain : A Journal of Neurology, 146(3), 1053–1064. https://doi.org/10.1093/brain/awac127

Srinivasan, S., Butters, E., Collins-Jones, L., Su, L., O’Brien, J., & Bale, G. (2023). Illuminating neurodegeneration: a future perspective on near-infrared spectroscopy in dementia research. Neurophotonics, 10(02). https://doi.org/10.1117/1.NPh.10.2.023514

Kershenbaum, A. D., Price, A. C., Cardinal, R. N., Chen, S., Fitzgerald, J. M., Lewis, J., Moylett, S., & O’Brien, J. T. (2023). Mortality rates and proximal causes of death in patients with Lewy body dementia versus Alzheimer’s disease: A longitudinal study using secondary care mental health records. International Journal of Geriatric Psychiatry, 38(5), e5937. https://doi.org/10.1002/gps.5937

Festari, C., Massa, F., Cotta Ramusino, M., Gandolfo, F., Nicolosi, V., Orini, S., Aarsland, D., Agosta, F., Babiloni, C., Boada, M., Borroni, B., Cappa, S., Dubois, B., Frederiksen, K. S., Froelich, L., Garibotto, V., Georges, J., Haliassos, A., Hansson, O., … Frisoni, G. B. (2023). European consensus for the diagnosis of MCI and mild dementia: Preparatory phase. Alzheimer’s & Dementia, 19(5), 1729–1741. https://doi.org/10.1002/alz.12798

Lam, B. Y. K., Cai, Y., Akinyemi, R., Biessels, G. J., Van Den Brink, H., Chen, C., Cheung, C. W., Chow, K. N., Chung, H. K. H., Duering, M., Fu, S. T., Gustafson, D., Hilal, S., Hui, V. M. H., Kalaria, R., Kim, S., Lam, M. L. M., De Leeuw, F. E., Li, A. S. M., … Mok, V. C. T. (2023). The global burden of cerebral small vessel disease in low- and middle-income countries: A systematic review and meta-analysis. International Journal of Stroke, 18(1), 15–27. https://doi.org/10.1177/17474930221137019

Malpetti, M., Jones, P. S., Cope, T. E., Holland, N., Naessens, M., Rouse, M. A., Rittman, T., Savulich, G., Whiteside, D. J., Street, D., Fryer, T. D., Hong, Y. T., Milicevic Sephton, S., Aigbirhio, F. I., O′Brien, J. T., & Rowe, J. B. (2023). Synaptic Loss in Frontotemporal Dementia Revealed by [ ¹¹ C ] UCB‐J Positron Emission Tomography. Annals of Neurology, 93(1), 142–154. https://doi.org/10.1002/ana.26543

Tsamourgelis, A., Swann, P., Chouliaras, L., & O’Brien, J. T. (2023). From protein biomarkers to proteomics in dementia with Lewy Bodies. Ageing Research Reviews, 83, 101771. https://doi.org/10.1016/j.arr.2022.101771

Hamilton, C. A., Gallagher, P., Ciafone, J., Barnett, N., Barker, S. A. H., Donaghy, P. C., O’Brien, J. T., Taylor, J.-P., & Thomas, A. J. (2023). Sustained attention in mild cognitive impairment with Lewy bodies and Alzheimer’s disease. Journal of the International Neuropsychological Society, 1–7. https://doi.org/10.1017/S1355617723000772

Mak, E., Zhang, L., Tan, C. H., Reilhac, A., Shim, H. Y., Wen, M. O. Q., Wong, Z. X., Chong, E. J. Y., Xu, X., Stephenson, M., Venketasubramanian, N., Zhou, J. H., O’Brien, J. T., & Chen, C. L.-H. (2023). Longitudinal associations between β-amyloid and cortical thickness in mild cognitive impairment. Brain Communications, 5(4), fcad192. https://doi.org/10.1093/braincomms/fcad192

Huang, W., Zeng, J., Jia, L., Zhu, D., O’Brien, J., Ritchie, C., Shu, N., & Su, L. (2023). Genetic risks of Alzheimer’s by APOE and MAPT on cortical morphology in young healthy adults. Brain Communications, 5(5), fcad234. https://doi.org/10.1093/braincomms/fcad234

Chen, S., Price, A. C., Cardinal, R. N., Moylett, S., Kershenbaum, A. D., Fitzgerald, J., Mueller, C., Stewart, R., & O’Brien, J. T. (2022). Association between antidementia medication use and mortality in people diagnosed with dementia with Lewy bodies in the UK: A retrospective cohort study. PLOS Medicine, 19(12), e1004124. https://doi.org/10.1371/journal.pmed.1004124

O’Brien, J. T., Chouliaras, L., Sultana, J., Taylor, J.-P., Ballard, C., on behalf of the RENEWAL Study Group, Aarsland, D., Blanc, F., Boeve, B., Brooks, D. J., Chaudhuri, K. R., Cummings, J., Feldman, H. H., Flicker, L., Galvin, J. E., Grosset, D. G., Ikeda, M., Kohlhaas, S., Lawlor, B., … Yarnall, A. (2022). RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia—an international Delphi consensus. Alzheimer’s Research & Therapy, 14(1), 169. https://doi.org/10.1186/s13195-022-01103-7

Markus, H. S., Van Der Flier, W. M., Smith, E. E., Bath, P., Biessels, G. J., Briceno, E., Brodtman, A., Chabriat, H., Chen, C., De Leeuw, F.-E., Egle, M., Ganesh, A., Georgakis, M. K., Gottesman, R. F., Kwon, S., Launer, L., Mok, V., O’Brien, J., Ottenhoff, L., … Dichgans, M. (2022). Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review. JAMA Neurology, 79(11), 1187. https://doi.org/10.1001/jamaneurol.2022.2262

Low, A., Prats-Sedano, M. A., McKiernan, E., Carter, S. F., Stefaniak, J. D., Nannoni, S., Su, L., Dounavi, M.-E., Muniz-Terrera, G., Ritchie, K., Lawlor, B., Naci, L., Malhotra, P., Mackay, C., Koychev, I., Ritchie, C. W., Markus, H. S., & O’Brien, J. T. (2022). Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study. Alzheimer’s Research & Therapy, 14(1), 154. https://doi.org/10.1186/s13195-022-01095-4

Pham, K., Mulugeta, A., Zhou, A., O’Brien, J. T., Llewellyn, D. J., & Hyppönen, E. (2022). High coffee consumption, brain volume and risk of dementia and stroke. Nutritional Neuroscience, 25(10), 2111–2122. https://doi.org/10.1080/1028415X.2021.1945858

Pflanz, C. P., Egle, M. S., O’Brien, J. T., Morris, R. G., Barrick, T. R., Blamire, A. M., Ford, G. A., Tozer, D., Markus, H. S., & on behalf of PRESERVE study group. (2022). Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease. Neurology, 10.1212/WNL.0000000000201018. https://doi.org/10.1212/WNL.0000000000201018

McCombe, N., Joshi, A., Finn, D. P., McClean, P. L., Roberts, G., O’Brien, J. T., Thomas, A. J., Kane, J. P. M., & Wong-Lin, K. (2022). Distinguishing Lewy Body Dementia from Alzheimer’s Disease using Machine Learning on Heterogeneous Data: A Feasibility Study. 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 4929–4933. https://doi.org/10.1109/EMBC48229.2022.9871714

Mehraram, R., Peraza, L. R., Murphy, N. R. E., Cromarty, R. A., Graziadio, S., O’Brien, J. T., Killen, A., Colloby, S. J., Firbank, M., Su, L., Collerton, D., Taylor, J. P., & Kaiser, M. (2022). Functional and structural brain network correlates of visual hallucinations in Lewy body dementia. Brain, 145(6), 2190–2205. https://doi.org/10.1093/brain/awac094

Schumacher, J., Ray, N. J., Hamilton, C. A., Donaghy, P. C., Firbank, M., Roberts, G., Allan, L., Durcan, R., Barnett, N., O’Brien, J. T., Taylor, J.-P., & Thomas, A. J. (2022). Cholinergic white matter pathways in dementia with Lewy bodies and Alzheimer’s disease. Brain, 145(5), 1773–1784. https://doi.org/10.1093/brain/awab372

Dounavi, M.-E., Low, A., Muniz-Terrera, G., Ritchie, K., Ritchie, C. W., Su, L., Markus, H. S., & O’Brien, J. T. (2022). Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults. Brain Communications, 4(3), fcac116. https://doi.org/10.1093/braincomms/fcac116

Holland, N., Malpetti, M., Rittman, T., Mak, E. E., Passamonti, L., Kaalund, S. S., Hezemans, F. H., Jones, P. S., Savulich, G., Hong, Y. T., Fryer, T. D., Aigbirhio, F. I., O’Brien, J. T., & Rowe, J. B. (2022). Molecular pathology and synaptic loss in primary tauopathies: an 18F-AV-1451 and 11C-UCB-J PET study. Brain, 145(1), 340–348. https://doi.org/10.1093/brain/awab282

Sidhom, E., O’Brien, J. T., Butcher, A. J., Smith, H. L., Mallucci, G. R., & Underwood, B. R. (2022). Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia. International Journal of Molecular Sciences, 23(4), 2021. https://doi.org/10.3390/ijms23042021

Henderson, C., Knapp, M., Stirling, S., Shepstone, L., High, J., Ballard, C., Bentham, P., Burns, A., Farina, N., Fox, C., Fountain, J., Francis, P., Howard, R., Leroi, I., Livingston, G., Nilforooshan, R., Nurock, S., O’Brien, J. T., Price, A., … Banerjee, S. (2022). Cost-effectiveness of mirtazapine for agitated behaviors in dementia: findings from a randomized controlled trial. International Psychogeriatrics, 34(10), 905–917. https://doi.org/10.1017/S1041610222000436

Ciafone, J., Thomas, A., Durcan, R., Donaghy, P. C., Hamilton, C. A., Lawley, S., Roberts, G., Colloby, S., Firbank, M. J., Allan, L., Petrides, G., Taylor, J.-P., O’Brien, J. T., & Gallagher, P. (2022). Neuropsychological Impairments and Their Cognitive Architecture in Mild Cognitive Impairment (MCI) with Lewy Bodies and MCI-Alzheimer’s Disease. Journal of the International Neuropsychological Society, 28(9), 963–973. https://doi.org/10.1017/S1355617721001181

Donaghy, P. C., Cockell, S. J., Martin-Ruiz, C., Coxhead, J., Kane, J., Erskine, D., Koss, D., Taylor, J.-P., Morris, C. M., O’Brien, J. T., & Thomas, A. J. (2022). Blood mRNA Expression in Alzheimer’s Disease and Dementia With Lewy Bodies. The American Journal of Geriatric Psychiatry, 30(9), 964–975. https://doi.org/10.1016/j.jagp.2022.02.003

Brown, R. B., Tozer, D. J., Loubière, L., Hong, Y. T., Fryer, T. D., Williams, G. B., Graves, M. J., Aigbirhio, F. I., O’Brien, J. T., & Markus, H. S. (2022). MINocyclinE to Reduce inflammation and blood brain barrier leakage in small Vessel diseAse (MINERVA) trial study protocol. European Stroke Journal, 7(3), 323–330. https://doi.org/10.1177/23969873221100338

Dounavi, M.-E., Newton, C., Jenkins, N., Mak, E., Low, A., Muniz-Terrera, G., Williams, G. B., Lawlor, B., Naci, L., Malhotra, P., Mackay, C. E., Koychev, I., Ritchie, K., Ritchie, C. W., Su, L., & O’Brien, J. T. (2022). Macrostructural brain alterations at midlife are connected to cardiovascular and not inherited risk of future dementia: the PREVENT-Dementia study. Journal of Neurology, 269(8), 4299–4309. https://doi.org/10.1007/s00415-022-11061-7

Sidhom, E., Padilla, M. S., Lewis, J., White, S., O’Brien, J. T., Mallucci, G. R., & Underwood, B. R. (2022). Trazodone and patient outcomes in dementia—Limitations of naturalistic cohort data. International Journal of Geriatric Psychiatry, 37(8), gps.5777. https://doi.org/10.1002/gps.5777

Kurapova, R., Chouliaras, L., & O’Brien, J. T. (2022). The promise of amplification assays for accurate early detection of α-synucleinopathies: A review. Experimental Gerontology, 165, 111842. https://doi.org/10.1016/j.exger.2022.111842

Donaghy, P. C., Firbank, M., Petrides, G., Lloyd, J., Barnett, N., Olsen, K., Heslegrave, A., Zetterberg, H., Thomas, A. J., & O’Brien, J. T. (2022). The relationship between plasma biomarkers and amyloid PET in dementia with Lewy bodies. Parkinsonism & Related Disorders, 101, 111–116. https://doi.org/10.1016/j.parkreldis.2022.07.008

Ziukelis, E. T., Mak, E., Dounavi, M.-E., Su, L., & T O’Brien, J. (2022). Fractal dimension of the brain in neurodegenerative disease and dementia: A systematic review. Ageing Research Reviews, 79, 101651. https://doi.org/10.1016/j.arr.2022.101651