Alzheimer’s disease (AD) is a neurological condition that most commonly affects people over 65. It causes a range of symptoms including memory loss, confusion, problems with movement and even personality changes. AD can be incredibly distressing for both the patient and their families, and it is thought to affect over 800 000 people in the UK. […]
New evidence of disrupted safety signalling in obsessive compulsive disorder
Accurate evaluation of threats in our environment enables us to choose and perform adaptive behaviours. However, responding flexibly to threatening stimuli can be challenging for those with mental illness. The combination of rigid threat estimation characterises most major anxiety disorders, and these symptoms are also observed amongst individuals suffering with obsessive compulsive disorder (OCD) alongside rigid behavioural […]
Advances in endophenotyping social anxiety disorder
Social anxiety disorder (SAD) is a disabling psychiatric disorder characterised by an excessive fear and avoidance of social situations. About 10 – 15% of individuals will develop SAD over the life-course, and while treatments such as cognitive behavioural therapy are effective for some, symptoms are often chronic and unremitting. Despite a pressing need, the biological […]