The Trial-Ready Cohort – Down Syndrome (TRC-DS) project is a programme that aims to address many current problems with clinical trial recruitment and group management for people with Down syndrome.
With TRC-DS, we’re aiming to create a smooth transition from monitoring visits to therapeutic (this means “helping against disease”) clinical trial participation and also ensure Alzheimer’s disease prevention clinical trials are performed more effectively for people with Down syndrome.
Here at Cambridge, we’ll be looking to recruit 8 or more people with Down syndrome between ages 35-55 years and follow up on their outcome measures (i.e., the results of their scans and tests) for about 16 months.
The scans and tests we’ll be doing for TRC-DS are similar to those for ABC-DS but there would be fewer, so overall the visits should be shorter and easier.
Enrolling in TRC-DS and being one of the participants for whom longitudinal (this means “over time”) health information would be recorded would allow participants to be included in future therapeutic clinical trials for preventing Alzheimer’s disease in people with Down syndrome. That’s where the study name comes from – the goal is to make a ‘Trial-Ready Cohort’ of people with Down syndrome!
If you’re interested in getting involved, please contact us via email: CIDDRG@medschl.cam.ac.uk