Submitted by la334 on Fri, 08/11/2024 - 11:26
Consultant psychiatrist and researcher Emilio Fernandez-Egea have published a statement with the president of the Royal College of Psychiatry and UK leaders in psychopharmacology in The British Journal of Psychatrydebunking the conception that clozapine is associated with high mortality.
While clozapine has risks, the relative risk of fatality is overestimated. The UK pharmacovigilance programme is efficient, but comparisons with other drugs can mislead because of reporting variations.
Clozapine actually lowers mortality, partly by reducing schizophrenia-related suicides, but preventable deaths still occur. Clozapine should be used earlier and more widely, but there should be better monitoring and better management of toxicity.
Read the Article: Mortality associated with clozapine: what is the evidence?
Consultant psychiatrist and researcher Emilio Fernandez-Egea has over 15 years of experience in private and NHS clinical activity and research at the Department of Psychiatry, University of Cambridge. General adult specialist with a particular interest in severe mental illness and psychotic disorders. He has more than a hundred academic publications, is a speaker at international academic conferences and recently in a TEDx talk. He also has ample experience leading clinical trials for public and commercial sponsors.